URINARY N-ACETYL-β-D-GLUCOSAMINIDASE ACTIVITY IN PATIENTS WITH URINARY TRACT DISEASES
نویسندگان
چکیده
منابع مشابه
Evaluation of Human Urinary N-acetyl beta – D- glucosaminidase index in children with urinary tract anomalies
Background: The kidneys perform glomerular filtration, tubular reabsorption, and tubular secretion and the study of urinary excretion of some enzymes considered as a sensitive test for the detection of early stages of renal disease, particularly N-acetyl-β-D-glucosaminidase (NAG) which is a hydrolytic lysosomal enzyme present in the epithelial cells of the proximal convoluted tubule. Increased ...
متن کاملIs urinary N-acetyl-beta-D-glucosaminidase a marker of urological abnormality in children?
Abstract Background: Hydronephrosis is the most common congenital condition that is detected by prenatal ultrasonography. Moreover, the widespread use of prenatal ultrasonography results in an increased recognition of fetal hydronephrosis. Prenatal hydronephrosis is diagnosed at an incidence of 1:100 to 1:500 by ultrasonographic studies. The presence of hydronephrosis is not synonymou...
متن کاملIncreased urinary N-acetyl-beta-D-glucosaminidase activity in children with hydronephrosis.
OBJECTIVE Hydronephrosis leads to deterioration of renal function. As urinary N-acetyl-beta-D-glucosaminidase (U-NAG) activity is considered a sensitive marker of renal tubular impairment, our aim was to measure U-NAG in children with hydronephrosis and to look for a relationship among selected clinical parameters. MATERIALS AND METHODS We studied 31 children (22 boys and 9 girls, mean age 2....
متن کاملThe Role of Urinary N-acetyl Beta-D-glucosaminidase in Children with Urological Problems.
OBJECTIVES To assess urinary NAG/ urinary creatinine (NAG/ Cr) ratio in patients with urological abnormalities (normal and abnormal ultrasonography) and compare it with normal healthy children. METHODS A prospective study was conducted from November 2012 to April 2013. Urine samples were collected from 70 patients with various urological abnormalities, and from 40 healthy control groups, thei...
متن کاملUrinary N-acetyl-beta-D-glucosaminidase isoenzyme activity as measured by fast protein liquid chromatography in patients with nephrotic syndrome.
Exactly why N-acetyl-beta-D-glucosaminidase (NAG) excretion is increased in patients with nephrotic syndrome with glomerular lesions is poorly understood. Glomeruli contain less NAG than do proximal tubules. In this study, we have tried to measure the NAG isoenzymes automatically by use of the recently developed fast protein liquid chromatography (FPLC) system, followed by column chromatography...
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ژورنال
عنوان ژورنال: The Japanese Journal of Urology
سال: 1984
ISSN: 0021-5287,1884-7110
DOI: 10.5980/jpnjurol1928.75.10_1595